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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sibvest</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский вестник сельскохозяйственной науки</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Herald of Agricultural Science</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-8799</issn><issn pub-type="epub">2658-462X</issn><publisher><publisher-name>Siberian Federal Scientific Centre of Agro-BioTechnologies of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26898/0370-8799-2025-9-6</article-id><article-id custom-type="elpub" pub-id-type="custom">sibvest-2286</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗООТЕХНИЯ И ВЕТЕРИНАРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ZOOTECHNICS AND VETERINARY MEDICINE</subject></subj-group></article-categories><title-group><article-title>Регулирование окислительного стресса как основа здоровья и продуктивности животных</article-title><trans-title-group xml:lang="en"><trans-title>Regulation of oxidative stress as the foundation for animal health and productivity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4663-2217</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бекенёв</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bekenev</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бекенёв Виталий Алексеевич, главный научный сотрудник, доктор сельскохозяйственных наук, профессор</p><p>Новосибирская область, р.п. Краснообск, ул. Центральная, 7</p></bio><bio xml:lang="en"><p>Vitaly A. Bekenev, Head Researcher, Doctor of Science in Agriculture, Professor</p><p>Bl. 7, Tsentralnaya St., Krasnoobsk, Novosibirsk Region</p></bio><email xlink:type="simple">bekenev39@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9520-8271</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаренко</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharenko</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захаренко Александр Михайлович, заместитель директора, ведущий научный сотрудник, кандидат химических наук</p><p>Новосибирская область, р.п. Краснообск</p></bio><bio xml:lang="en"><p>Alexander M. Zakharenko, Deputy Director, Lead Researcher, Candidate of Science in Chemistry</p><p>Krasnoobsk, Novosibirsk region</p></bio><email xlink:type="simple">zakharenko@sfsca.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Сибирский федеральный научный центр агробиотехнологий Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian Federal Scientific Centre of Agro-BioTechnologies of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2025</year></pub-date><volume>55</volume><issue>9</issue><fpage>53</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бекенёв В.А., Захаренко А.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Бекенёв В.А., Захаренко А.М.</copyright-holder><copyright-holder xml:lang="en">Bekenev V.A., Zakharenko A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://sibvest.elpub.ru/jour/article/view/2286">https://sibvest.elpub.ru/jour/article/view/2286</self-uri><abstract><p>Изложены результаты собственных исследований и обзор литературных источников по проблемам адаптации животных к факторам внешней среды, особенно к интенсивным методам разведения животных, с позиций работы митохондрий, свободнорадикального окисления тканей и энергетического обмена. Базируясь на фундаментальных исследованиях о состоянии биофизического потенциала живой системы, показано влияние перекисного окисления липидов на состояние здоровья, продуктивность, жизнеспособность животных и роль антиоксидантов в их проявлении. Снижение прироста, возникающее у поросят при отъеме от матерей, связанное с перекисным окислением липидов, можно устранять с помощью различных видов антиоксидантов. Разработаны дозы ультрафиолетового облучения свиней в условиях промышленной технологии, позволяющие регулировать уровень свободнорадикального окисления тканей и усиливать их антиоксидантную активность, улучшать плодовитость свиноматок, жизнеспособность и интенсивность роста приплода. Впервые обнаружены резкие различия наиболее распространенных пород свиней по уровню свободнорадикального окисления их тканей, связанные с различным содержанием жирных кислот и холестерина во внутримышечном жире и сале. Показана зависимость качества мясных продуктов от состава их жирных кислот. Такие антиоксиданты, как каталаза и тиоловые соединения, содержащиеся в крови хряков и свиноматок, способны противодействовать разрушающему воздействию активных форм кислорода при оплодотворении, влияют на плодовитость, массу гнезда при опоросе. Впервые в противоположность сложившемуся стереотипу о вредности НЖК, в частности сала свиней, экспериментальным путем доказано, что жир, содержащий больше НЖК, но меньше ПНЖК, особенно линолевой жирной кислоты и холестерина, при включении в корм животных положительно влияет на продуктивность и сердечно-сосудистую систему, снижает атерогенный индекс. Предложено ввести специальный раздел животноводства «Энергобиотест», изучающий соотношение окислительных и антиоксидантных реакций в организме, проводящий разработку техно- логий гармонизации жизненных процессов и улучшения качества продукции животноводства.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of the authors' own research and a review of literature sources on the issues of animal adaptation to environmental factors, particularly intensive animal farming methods, from the perspective of mitochondrial function, tissue free-radical oxidation, and energy metabolism. Based on fundamental studies of the biophysical potential state of living systems, the influence of lipid peroxidation on health status, productivity, and viability of animals is demonstrated, along with the role of antioxidants in their manifestation. The decrease in growth that occurs in piglets at weaning, associated with lipid peroxidation, can be eliminated with the help of various types of antioxidants. Doses of ultraviolet irradiation of pigs under the conditions of industrial technology have been developed, which make it possible to regulate the level of free-radical oxidation of tissues and enhance their antioxidant activity, allowing to improve the fertility of sows, the viability and intensity of growth of the offspring. For the first time, sharp differences in the most common breeds of pigs in the level of free-radical oxidation of their tissues have been found, associated with different content of fatty acids and cholesterol in intramuscular fat and lard. The dependence of the quality of meat products on the composition of their fatty acids has been shown. Antioxidants such as catalase and thiol compounds contained in the blood of boars and sows are able to counteract the destructive effect of reactive oxygen species during fertilization, affect fertility and the litter weight during farrowing. For the first time, in contrast to the stereotype about the harmfulness of EFAs and, in particular, pork lard, it has been experimentally proven that fat containing more EFAs, but less PUFAs, especially linoleic fatty acid and cholesterol, when included in animal feed, has a positive effect on productivity and the cardiovascular system, and reduces the atherogenic index. It has been proposed to introduce a special section of animal husbandry, "Energobiotest", which studies the ratio of oxidative and antioxidant reactions in the body, develops technologies for harmonizing life processes and improving the quality of livestock products.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>свиньи</kwd><kwd>жир</kwd><kwd>митохондрия</kwd><kwd>окислительный стресс</kwd><kwd>УФ-облучение</kwd><kwd>каталаза</kwd><kwd>жирные кислоты</kwd><kwd>антиоксиданты</kwd><kwd>тиоловые соединения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pigs</kwd><kwd>fat</kwd><kwd>mitochondria</kwd><kwd>oxidative stress</kwd><kwd>UV- irradiation</kwd><kwd>catalase</kwd><kwd>fatty acids</kwd><kwd>antioxidants</kwd><kwd>thiol compounds</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Воейков В.Л. 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