COMPARATIVE ANALYSIS OF EFFICACY OF ANTHELMINTHICS IN FARM-SCALE TRIALING

Abstract

Results are given from a scientific-production experiment carried out at a commercial maral farm. The work was done at the “Pole” Co Ltd, Altai District, Altai Territory, and at the Animal Infectious Disease Laboratory of the All-Russian Research Institute for Antlered Deer Farming, Barnaul, Altai Territory. The experiment was carried out on spontaneously infested animals (70 young marals and 100 maral stags) during conducting the spring veterinary-sanitary measures. Invasion diseases among antlered deer population in Altai Territory and the Republic of Altai are widely spread causing economic damage to the maral farming because of our failure to obtain maximum products. The growth in antlered deer population and high concentration of animals per unit of area create a favorable environment for developing helminth fauna. Among the variety of helminth fauna, elaphostrongyliosis and intestinal strongylatoses are most wide-spread. The causative agents of these diseases, against the background of long-term use of drugs from the family of macrocyclic lactones, yield the resistance to them that requires searching new anthelminthics and using them at scientifically-grounded dates. When studied the efficacy of antiparasitic drugs, an on-farm maral experiment with the use of two different drugs, closalben and eprimek, was conducted. The extensive and intensive efficacy of these anthelminthics was evaluated under on-farm conditions at elaphostrongyliosis and intestinal infections in marals. It has been established that the injection preparation eprimek yields to the powdery preparation closalben in the efficacy at both elaphostrongyliosis and intestinal infection.